<br>The exception to the rule is the DOT1 household, members of which methylate K79 in the globular region of histone H3 and which are structurally not associated to [SET-area proteins](https://repo.komhumana.org/luciaalicea728/solicitor-law-firms1988/wiki/Dieting-Ideas-For-Lazy-Bones) 4 - 6 Current work suggests that SET-area-containing proteins methylate a couple of proteins along with histones (see later)