Lots of folks feel pressured to drop some weight and try different types of diets. It has been common for a long time in cold areas akin to Northern France - Brittany (savory buckwheat crepes are their speciality), Russia (the little pancakes known as blinis had been traditionally made with buckwheat), and Northern China - later introduced to Japan, (soba noodles).

The exception to the rule is the DOT1 family, members of which methylate K79 in the globular area of histone H3 and which are structurally not related to SET-domain proteins four - 6 Current work suggests that SET-area-containing proteins methylate a couple of proteins along with histones (see later)